Abstract:Sodiumsulphite (saltprecipitation)assay ,heatprecipitationassay ,immunoturbidityassayandthePT dermethod ,whichare commonlyusedforfibrinogenassayinclinicallaboratoriesofChina ,werecomparedwiththevonClaussmethodrespectively .Theresults showedthatthedifferencebetweenphysiochemicalmethodsandthevonClaussmethodwaslargerthanthatbetweenthePT dermethodandthe vonClaussmethod .ItsuggestthatthevonClaussmethod ,whichismorerapid ,easier ,andmoreaccurate ,bepromotedasaroutine methodforclinicallaboratoriesofChina .