Abstract: Objective：To investigate the distribution of the mobile genetic elements, including integrons, transposons, insertion sequences and conjugative plasmids, in Acinetobacter baumannii carried with bla_ADC gene. Methods: One hundred and seventy-nine isolates of Acinetobacter baumannii were collected, and their bla_ADC gene was determined by PCR. Then, four kinds of mobile genetic elements, including integron genetic marks such as intI 1, intI 2, intI 3 and qacE△1-sul1, transposon genetic marks such as merA, tnpU, tnp513 and tnpA, insertion sequence genetic marks such as ISAba1 and IS26, and conjunction plasmid genetic marks such as traA and trbC, and the antimicrobial susceptibility of the isolates with bla_ADC gene were detected by PCR and the disk diffusion method, respectively. Results：There was 117 isolates of Acinetobacter baumannii carried with bla_ADC gene in all 179 isolates. Among them, the positive rates of intI 1, qacE△1-sul1, merA, tnpU, tnp513, ISAba1 and IS26 were 71.8%, 98.3%, 94.9%, 93.2%, 76.9%, 98.3% and 100.0%, respectively, and the other 5 genes were negative. There were at least 3 and at most 7 mobile genetic marks to be detected for each of 117 isolates, and the isolates with 3 and 7 mobile genetic marks accounted for 0.9% and 50.4%, respectively. Conclusion：Mobile genetic elements can be easily detected from the Acinetobacter baumannii carried with bla_ADC, and its drug resistance may be related to the existence of mobile genetic elements.