Abstract：Objective：To establish a networked information management system for clinical laboratories in community of Suzhou and evaluate its clinical application. Methods：Based on dedicated network of public health information in Suzhou City, laboratory information management system (LIS) and hospital information management system (HIS), the management for centralized detections of clinical samples from the health institutions of intraregional community were performed as the key mission, and a regional, networked and informationized management system was designed for the clinical laboratories of community. Results：The informationized management of whole process including test application, specimen collection, delivery and receiving, report releasing and payment, etc. was achieved on line. The information of clinical laboratories among the communities was transferred and shared in whole Suzhou City. Conclusion：The established system should be safe, convenient and efficient online networkbased information management system between the Suzhou clinical laboratory center and the laboratories in each local community, by which the centralized detections in the clinical laboratories of community could be performed readily.