Abstract: Objective To evaluate the screening results of early diagnosis and treatment of cancer in Liangxi District, Wuxi City from 2022toandpovidabasisfortheseningofarlcanceMetshpoplatinpacipatigintprojcofearldg nosis and treatment of cancer in Liangxi District,Wuxi City from 2022 to 2023 were selected as the survey subject. The high-risk population were evaluated by the developed risk factor questionnaire and further performed the early screening for lung cancer, upper gastrointestinalcancer,livercancer,andcolorectalcancer.Thehigh-risk rate，screening participationrate，and positivelesiondetectionrate of each cancer were calculated. ResultsA total of 21 652 individuals in Liangxi District,Wuxi City from 2022 to 2023 completed the risk factor questionnaire. Among them,12 201 were identified as high-risk individuals. The overall high-risk rate was 56.35%，including58.36formalesand55.12forfemales.Thehigh-riskratesforlungcancercolorectalcanceruppergastrointestinalcancer andlivercancerwere33.9118.8717.86and4.28respectively.Atotalof1759individualscompletedclinicalscreening, and the participation rates for each type of cancer were ranked from high to low as liver cancer (21.36%）,lung cancer (17.60%），upper gastrointestinal cancer(4.19%)，and colorectal cancer(2.62%). A total of 220 positive lesions were detected,with a positive lesion detection rate of 12.51%. ConclusionIn the early diagnosis and treatment of cancer in Liangxi District,Wuxi City from 2022 to 2023,the participation rateof clinicalscreeningfor each typeofcancerisnot high,and thedetectionrate of positivelesionsis also low. There is a need to further improve the early screening methods of cancer to increase the detection rate for early-stage cancers.